Science is increasingly collaborative. As the frontiers of our knowledge expand, pushing them further increasingly relies on the efforts of numerous scientists drawing on each others' abilities. 
Modern cyberinfrastructures are learning how to work in this overlapping, interlocking world by focusing on the interactions of people. To do this, they draw on lessons learned from popular existing websites, such as Flickr and YouTube, where users share and rate and remix images and videos.

With arXiv, scientists share preprints. With Connotea, Bibsonomy, and CiteULike, anybody can manage references in a collaborative fashion.  With Swivel and ManyEyes, people upload data sets and generatevisualizations. With nanoHUB, nanoscientists share algorithms and knowledge. With Network Workbench and CIShell, there is a common platform to plug and play algorithms. These and many more e-Science projects and cyberinfrastructures for diverse scientific communities 
are making the inter actions of people the drivers of their innovation.  That is the future of a modern cyberinfrastructure that enables innovative and impactful science.

This talk will discuss modern e-Science projects and cyberinfrastructures, and how they make it possible for scientists to contribute, rate, remix, and collaborate. It will discuss the new frontiers of cyberinfrastructure, in particular how they relate to scientists, policy makers, and the public, and conclude with a vision of science performed in a mashed-up, cloud-based IT world.