The Knowledge Networks (KNs) of the World Health Organization, Commission on Social Determinants of Health are its primary mechanisms for learning and knowledge synthesis. The globalization KN adopted Jenkins definition of globalization as a process of greater integration within the world economy through movements of goods and services, capital, technology and (to a lesser extent) labour, which lead increasingly to economic decisions being influenced by global conditions.Thirteen commissioned research syntheses papers were produced over a 16 month period, addressing such issues as econometric modeling of globalization-driven changes in health outcomes, trade, global financial flows, labour market adjustments, globalized health sector reforms, health worker migration, food security, water/sanitation, global governance and effects on national  policy space. This presentation will focus on key findings and policy recommendations emanating from the globalization KN final report, with a focus on social and econom ic vulnerabilities as they affect a wide range of groups.